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Filtered Search Results
Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 200mg, CAS: 155141-29-0.
Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | MFCD20526769 | 99.8% | 508.56 g/mol | C28H32N2O7 | 5 MG
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Indacaterol maleate is the maleate salt of indacaterol, an ultra-long-acting β2-adrenergic receptor agonist. Supplied as an analytical standard, this solid reference material is intended for research use in assay development, method validation, and quality control testing.
- High purity (99.8%).
- Suitable for assay development and method validation.
- Confirmed identity by LC-MS consistent with structure.
- Stable solid form for accurate weighing and storage.
- Includes CAS 753498-25-8 and molecular weight 508.56 g/mol.
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.3% | 455.54 | 1 ML
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent antagonist of the NMDA receptor containing the NR2B subunit. It demonstrates anticonvulsant and anti-parkinsonian activity, making it a valuable compound for Parkinson's disease research.
- Potent and selective NMDA receptor antagonist
- Specific for NR2B subunit
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Useful for Parkinson's disease research
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eMolecules 91388-25-9 | 1-Bromo-2-(2-methyl-propenyl)-benzene | J & W PharmLab LLC | MFCD29034263 | 211.102 | C10H11Br | 96.000 | CC(C)=Cc1ccccc1Br | 1g | 448727036
1-Bromo-2-(2-methyl-propenyl)-benzene | J & W PharmLab LLC | 91388-25-9 | MFCD29034263 | 211.102 | C10H11Br | 96.000 | CC(C)=Cc1ccccc1Br | 1g | 448727036
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.88% | 541.58 | 1 ML
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Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It can effectively inhibit the activities of JAK1, JAK2, JAK3, and TYK2. This compound also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Selective, orally available JAK1 inhibitor
- Anti-inflammatory and antiviral activities
- Inhibits activities of JAK1, JAK2, JAK3, and TYK2
- Inhibits HIV-1 driven gene transcription
- Reduces proliferation of HIV-1 infected cells
- Suitable for research in rheumatoid arthritis and inflammatory bowel disease
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Medchemexpress LLC Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 100 MG
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Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 100 MG
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eMolecules 2828446-92-8 | Ambeed | 2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(4455-tetramethyl-132-dioxaborolan-2-yl)thiazole | 100mg | 491657158 | A307802 | MFCD19689425 | 355.38 | C16H30BNO3SSi
Ambeed | 1-Methyl-2-oxo-12-dihydropyridine-4-carbonitrile | 100mg | 518523937 | A126143 | 70411-83-5 | MFCD27923636 | 134.138 | C7H6N2O
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 50mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 25 MG
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Avitinib maleate is a third-generation, irreversible, and orally active selective EGFR inhibitor. It has IC50 values of 0.18 nM against both EGFR L858R and EGFR T790M, and 7.68 nM against wild-type EGFR. It is also a BTK inhibitor, inducing apoptosis and inhibiting BTK phosphorylation in mantle cell lymphoma. It exhibits anticancer effects.
- Third-generation, irreversible, and orally active selective EGFR inhibitor.
- Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
- BTK inhibitor.
- Induces apoptosis.
- Inhibits phosphorylation of BTK in mantle cell lymphoma.
- Exhibits anticancer effects.
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Medchemexpress LLC Setiptiline maleate | 85650-57-3 | 99.9% | 377.43 | 50 MG
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Setiptiline maleate is a serotonin receptor antagonist and a tetracyclic antidepressant (TeCA) that acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
- Functions as a norepinephrine reuptake inhibitor.
- Acts as an α2-adrenergic receptor antagonist.
- Serves as a serotonin receptor antagonist, targeting 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes.
- Acts as an H1 receptor inverse agonist/antihistamine.
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TARGETMOL CHEMICALS INC ACEPROMAZINE MALEATE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ACEPROMAZINE MALEATE is a dopamine receptor antagonistpurity: 99%
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Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 10mM (in 1mL DMSO), CAS: 155141-29-0.
Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 100 MG
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-HT1A receptor antagonist used for pharmacology and receptor-binding research. It is provided as a high-purity analytical standard suitable for in vitro and in vivo studies.
- Potent 5-HT1A receptor antagonist (IC50 = 0.91 nM; Ki = 0.39 nM).
- High purity: 99.6% (HPLC).
- Molecular weight 538.64 g/mol.
- Molecular formula C29H38N4O6.
- Supplied as a 100 mg vial for research use.
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Cayman Chemical Betulin 3,28-diacetate, Purity: ≥95%, CAS: 1721-69-3, 10 mg
A triterpene with antiviral and hepatoprotective activities; inhibits SFV replication in virus-infected Huh7 cells (IC50 = 9.1 µM); improves hepatic function in various rat models of hepatitis at 20 mg/kg
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